Can calorie restriction help you live longer? If you do this, it will have the opposite effect.

a toothThe Jackson Lab/Calico Life Science research team conducted animal experiments on 960 mice
a toothA calorie-restricted diet has a significant effect on life extension
a toothLosing too much weight shortens your life.

Research results have been published on the effects of calorie restriction and fasting on life. The results of this study (Dietary effects on the health and lifespan of genetically diverse mice) were recently published in the international academic journal ‘Nature’.

intermittent fasting on longevity Source: Midjourney”/>Research results have been published on the effects of calorie restriction and intermittent fasting on longevity Source: Midjourney
A research team from The Jackson Laboratory and Calico Life Sciences compared the effects of calorie restriction and intermittent fasting in more than 1,000 genetically different female mice. The researchers wanted to know how widespread the effect was for a diet known to extend life, such as calorie restriction or fasting.

The mice were divided into five groups and assigned to eat different diets: a control group that restricted daily calorie intake to 60% or 80% of baseline, fasted for a day or two after each other every week without calorie restriction, or a control group that ate. as much as they can without any restrictions.

The results of the study showed that both calorie restriction and intermittent fasting had a significant effect on life extension, but the effects differed according to genetic factors.

The average lifespan of mice whose daily caloric intake was restricted to 80% or 60% of baseline was 30 and 34 months, indicating that the calorie-restricted diet was the most effective in ‘life extension. However, mice that lost a lot of weight during the period of dietary restriction had a shorter lifespan. The average life span of mice that went through fast fasting was 28 months, which had the effect of extending their life span compared to the control group, which had an average life span of 25 months, but there was no significant effect seen in mice with high initial body weight.

The research team expected that extreme dietary restrictions, such as a 40% calorie restriction or fasting for two days in a row, might have a negative effect on some mice, but they found that a life-extending effect was seen in the – all cases.

The researchers found that dietary restrictions have good health effects, including reducing the risk of obesity, but at the same time, maintaining body weight and body fat can be important factors in longevity. This is a result that goes against established theory, meaning that weight loss may not extend life.

In addition, they found that a calorie-restricted diet affects the immune system and blood parameters such as red blood cell distribution width (RDW). Dietary restrictions have long-term effects on health and longevity through changes in the immune system and red blood cells.