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The effectiveness of the fourth dose of covid vaccine lasts less than the third

A fourth dose of the Pfizer vaccine provides additional protection against SARS-CoV-2 infection and severe Covid-19 illness in relation to the three doses of the vaccine. However, the relative efficacy of the fourth dose against the disease appears to decline earlier than that of the third dose. This is the main conclusion of the study carried out by the Kahn Sagol Maccabi Research and Innovation Center in Tel Aviv, which examines the relative efficacy of a fourth dose of BNT162b2 compared to three doses over a period of 10 weeks.

The analysis, led by Sivan Gazit and published in BJM, included 97,499 people aged 60 or over, who were eligible to receive a fourth dose of the vaccine and obtained at least one polymerase chain reaction (PCR) test. ) during the study. Of these, 27,876 received a fourth dose of the Pfizer covid vaccinewhile 69,623 received only three doses.

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