On the largest courts with a retractable roof, Karolína Muchová will play against the American Danielle Collins in the Margaret Court Arena, and Petra Kvitová will play against the Ukrainian Anhelina Kalinin in the John Cain Arena.
Barbora Krejčíková has French qualifier Clara Burelová as her opponent in the second round, Jiří Leheček will challenge American Christopher Eubanks, and Dalibor Svrčina, who advanced from the qualifiers, will try to get past 31st-seeded Yoshihito Nishioka from Japan.