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Artificially Grown Skin Organoids: A Breakthrough in Monkeypox Virus Research and Treatment

Research by the Leiden University Medical Center (LUMC) and the Erasmus MC shows that artificially grown skin, or skin organoids, are extremely suitable for researching the monkeypox virus and testing new treatments against it. Monkey pox behaves almost the same as in real skin. The LUMC reports this.

The organoids could support the entire life cycle of the monkeypox virus, researchers say about infecting the artificially grown skin with monkey pox. “Mpox was able to infect cells and use them to create new virus particles, which in turn were able to infect other cells,” said researchers Spiros Pachis and Penfei Li. Treatment of the virus with tecovirimat (a virus inhibitor) appears to inhibit the virus particles in the artificial skin.

Laboratory animals

Researchers previously conducted research into monkey pox using laboratory animals and cell lines, but researchers from the LUMC and Erasmus MC believe that skin organoids are currently the best instrument to test what happens to real skin with monkey pox. It is therefore expected that artificially grown skin will be used more often for research into monkeypox, how the skin reacts to it and the effectiveness of new medicines.

Also read: What do we know about the monkeypox virus in Europe?

By: National Healthcare Guide / Johanne Levinsky

2023-10-17 06:00:00
#laboratory #animals #needed #research #monkeypox #virus

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