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ANMAT Approval of Vaccine Qdenga o TAK-003: Protection Against Dengue Disease

The ANMAT – National Administration of Medicines, Food and Medical Technology, approved the use of the vaccine Qdenga o TAK-003 against dengue, developed by the Japanese laboratory Takeda. This vaccine seems to be a great protection against this disease that, according to World Health Organization (WHO), causes around 20,000 deaths and 390 million infections globally.

More than 20,000 volunteers participated in its research and it took around five years of development; during that period its safety and effectiveness appear to have been confirmed. The results showed that the vaccine managed to reduce hospitalizations by 84% and cases of symptomatic dengue by 61%.

It is an application of two doses at an interval of three months, it can be given to all people over 4 years of age whether or not they have had the disease and, although they are mild, it usually produces some reactions such as pain and redness in the injection site, headache, muscle pain, general malaise and weakness. All of these effects proved to be temporary in those volunteer participants in the vaccine testing and are related to its own mechanism of action.

What is a vaccine? live attenuated virus?

These types of vaccines use a weakened (or attenuated) form of the germ that causes the disease. Because vaccines are so similar to the natural infection they help prevent, they create a strong, long-lasting immune response. Although they can protect throughout life, their application is contraindicated in many cases.

The dengue vaccine, being a live attenuated virus, cannot be given to pregnant or breastfeeding women; people who use medications that affect the immune system, such as high-dose corticosteroids; people undergoing chemotherapy treatment; and, people with a weak immune system, this may be due to a genetic defect or human immunodeficiency virus (HIV) infection.

He Dr. Alberto Davidovich, Medical Director of Emerger, considers that, although this vaccine represents a new prevention tool, it should not be the only one. This viral disease is transmitted by a mosquito (Aedes Aegypti) that feeds on the blood of a person sick with dengue and then bites others. Contagion occurs only through the bite of infected mosquitoes, never from one person to another, nor through objects or breast milk.

This is why it is essential to continue using strategies to control and eliminate mosquito breeding sites; avoid collecting water in outdoor containers so that they do not become breeding grounds; properly cover water tanks and reservoirs; avoid accumulating garbage; apply repellents to prevent bites; and, place spirals or mosquito nets.

Like 29 years ago, EMERGER GROUP keep providing Health services pre-hospital excellence and adding added value to the entire community in general in terms of prevention and care.

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2023-11-22 03:03:24
#Emerge #Dengue #Vaccine

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