An abnormal gene can make the brain too big or too small

Scientists tested the function of ZNRF3 in the laboratory. They created defective versions of the gene and found that disrupting RING increased the Wnt signaling pathway, which is needed to produce a certain number of brain cells. And if the mutation is in the RSPO category, the situation will be the opposite. In this case, the number of signals is reduced, which is why the brain does not grow to the desired size. Scientists noted that the work of Wnt can be influenced by using specific methods. However, they say this must be approached with extreme caution.