Home » Health » A new study from Uppsala University has found that patients treated with blood pressure-lowering medications can experience greater improvements from a change of medication than from doubling the dose of their current medication. The study suggests that there is an optimal blood pressure drug for each individual which could lead to personalised treatment plans. These findings challenge the strategy in current treatment guidelines where four drug groups are recommended equally for all high blood pressure patients.

A new study from Uppsala University has found that patients treated with blood pressure-lowering medications can experience greater improvements from a change of medication than from doubling the dose of their current medication. The study suggests that there is an optimal blood pressure drug for each individual which could lead to personalised treatment plans. These findings challenge the strategy in current treatment guidelines where four drug groups are recommended equally for all high blood pressure patients.

High blood pressure, also known as hypertension, is a leading cause of heart disease and stroke. Unfortunately, many people who have hypertension do not know they have it, and even when they do, finding the right medication to keep their blood pressure under control can be a challenge. However, recent advancements in personalized drug therapy show promise in providing maximum benefit for those with hypertension. In this article, we will explore the benefits and the science behind personalized drug therapy for hypertension.


A new study from Uppsala University suggests that patients treated with medication to lower blood pressure could benefit more from changing to a different medication rather than doubling the dose of their current medication. The study could lead to personalised blood pressure treatments for individual patients.

The study involved 280 patients from Sweden who tested four different blood pressure-lowering medications over the course of a year to determine which medication provided the best results for their individual needs. The study found that patients experienced twice the effectiveness from switching to an alternative medication than they did by doubling their current dose. It was also noted that specific individuals experienced lower blood pressure following the use of one medication in comparison to another.

More than two million Swedes presently have high blood pressure, and over half are unable to control their condition with medication. Up to half of those taking medication do not take their dosages as intended, raising the possibility of a lack of understanding of the efficacy of different medications.

This study challenges the current recommendation in treatment guidelines which suggest four drug groups equally as a possible treatment for all patients with high blood pressure. The study shows that personalising a patient’s medication can result in a better effect than random selection from one of these four drug groups. A specific blood pressure drug could possibly lower patients’ blood pressure more effectively and quickly, providing better protection against future cardiovascular diseases.

The study’s results indicate that there may be a more significant opportunity for personalised blood pressure treatments for individual patients. Personalisation in drug treatments, which take into account the genetic and environmental factors of an individual, may be crucial in leading to more precise and effective medication use in the future. Further studies will aid in confirming if personalised blood pressure-lowering medications would lead to better patient outcomes.


In conclusion, personalized drug therapy for hypertension is a promising approach that has the potential to provide maximum benefit to patients with high blood pressure. With numerous factors impacting an individual’s response to medication, including genetics, lifestyle, and coexisting health conditions, a one-size-fits-all approach is no longer sufficient in managing hypertension. Personalized medicine offers a more tailored approach to ensuring patients receive the medications that are most effective for them, while minimizing the risk of adverse effects. By incorporating this approach into hypertension management strategies, healthcare providers can improve outcomes for their patients with high blood pressure, ultimately leading to better health outcomes and improved quality of life.

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