Home » Health » A drug improves 45% of tumors of a type of early breast cancer – Society

A drug improves 45% of tumors of a type of early breast cancer – Society

The results of the SOLTI-TOT-HER3 study in patients with an early and aggressive type of breast cancer show that a single dose of the drug patritumab deruxtecan produces an improvement in tumors in 45% of the women studied.

In the fight against breast cancer, the most frequently diagnosed tumor among women, great efforts continue to be devoted to developing new treatments that help increase the available arsenal.

One of the lines that is achieving the best results is the one that combines an antibody with a chemotherapy drug, which is known as an antibody-drug conjugate or ADC, and which works in the following way: it is administered intravenously and travels through the blood to the tumor cells, where the antibody recognizes the entry point of these malignant cells, enters and releases the chemotherapy it carries to destroy them.

This is the case of patritumab deruxtecan, which has been studied in patients with previously untreated hormone-sensitive (HR+) and HER2-negative (HER2-) early breast cancer.

The results of the TOT-HER3 study, led by the president of the SOLTI research group, Aleix Prat, have been presented at the European Society for Medical Oncology ESMO Breast Cancer 2022 congress in Berlin.

The researchers have confirmed that, thanks to the drug, biological changes such as the infiltration of immune cells in the tumor, a decrease in proliferation and a high antitumor activity with tumor reduction occur in 45% of the patients included in the study.

Leave a Comment

This site uses Akismet to reduce spam. Learn how your comment data is processed.