American scientists have discovered a drug that is effective against both COVID-19 and cancer. Experts from the University of Southern California (USC) Keck School of Medicine have published their findings.
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Researchers have found that as a viral infection progresses, infected cells produce higher levels of the GRP78 protein. Using a special tool, the scientists suppressed GRP78 production in human lung cells in the laboratory without disrupting other cellular processes. The cells were then infected with SARS-CoV-2.
It turned out that the virus started producing less of the spike protein needed to enter cells. This suggests that GRP78 is required for the replication and production of pathogens.
They then used the recently developed anticancer drug HA15, which inhibits the activity of GRP78. The substance has shown high efficacy against the coronavirus. It is important that at the same time it did not have a detrimental effect on healthy cells. Experiments were carried out on mice, which showed a positive result.
Previously, Americans took up arms against red meat. According to a study by Dr. Marios Giannakis of the American Dana-Farber Cancer Institute, eaters of red meat are at risk of cancer.
Russian doctors discuss with US colleagues. In their opinion, cold cuts, semi-finished meat products and canned meat are more dangerous.
