A child who cannot tolerate excessive appetite… If this disease exists, it must be treated early.

If your baby is unable to drink milk well during the newborn period and develops obesity due to excessive appetite around the age of 2 or 3, it may be a rare hereditary disease called called Prader-Willi syndrome. Experts advise that if you have this disease, which makes it difficult to suppress your appetite and may slow down the development of cognitive function, there is a lot of room for improvement if you start treatment as early as possible. possible.

Prader-Willi syndrome, which occurs in 1 in 25,000 to 30,000 people, is characterized by a strong obsession with food because you do not feel full no matter what you eat. Because it is difficult to suppress one’s food, obesity and diabetes appear. During the newborn period, the baby has poor muscle tone, cannot drink the bottle well, has a weak cry, or does not cry often, but when he enters childhood, it shows symptoms such as excessive appetite, obesity, and developmental delay. Beginning around age 13, intellectual disability, behavioral disorders, and hypogonadism may also appear.

Dae-Hyeon Jang, professor of rehabilitation medicine at Incheon St. and various endocrine disorders can occur together,” adding, “If left without proper diagnosis and treatment, a short profile can occur.”

The cause of this disease is an abnormality in chromosome 15. The deletion type, which accounts for 60-70% of the total, occurs as a result of a microdeletion on chromosome 15. Another cause is chromosome 15, which is supposed to be inherited once from each parent, is inherited only from the mother, which accounts for about 20 to 30% of cases. In addition, in rare cases, there may be a mutation in the imprinting center of chromosome 15 inherited from the father.

Diagnosis varies depending on the genetic cause, but most cases can be diagnosed through DNA methylation analysis. However, there is still no specific treatment method. Nevertheless, if treatment and management starts from an early stage, the prognosis is likely to improve, so an accurate diagnosis should be made as early as possible before treatment. The treatment process necessarily includes growth hormone treatment, developmental rehabilitation treatment, and nutritional counseling In addition, depending on the symptoms, treatment at pediatric ophthalmology, pediatric otolaryngology may be required , pediatric urology, or pediatric psychiatry.

Prader-Willi syndrome is particularly difficult to manage, so it is best to maintain a diet to control excess appetite as much as possible and adhere to lifestyle rules such as exercise and vitamin intake D to prevent osteoporosis. Prof. said. .”