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A blood type that is more likely to have an early stroke

21:00

Friday 06 January 2023

A recent study reported that there is a blood type that can influence the risk of early stroke.

The study said, according to the Science Alert website, that people who have blood type A are more likely to have a stroke before age 60 than people who have other blood types.

The study, prepared in 2022, which included genomic research, showed a clear relationship between the A1 subgroup gene and early stroke.

The researchers combined data from 48 genetic studies, which included nearly 17,000 people who had had a stroke and nearly 600,000 people without strokes. The ages of all participants ranged from 18 to 59 years.

The study found that people whose genomes were coded for a variety of blood types were 16 percent more likely to have a stroke before age 60, compared with a group of other blood types.

For those with the O1 group gene, the risk was 12 percent lower.

However, the researchers noted, the additional risk of stroke in people with type A blood is small, so there’s no need for extra vigilance or screening in this group.

“We don’t yet know why type A blood poses a higher risk,” said Stephen Kitner, senior author of Neurology and Vascular Sciences at the University of Maryland, in a 2022 statement.

“But it’s likely related to blood clotting factors such as platelets, the cells that line blood vessels, as well as other circulating proteins, all of which play a role in blood clot formation,” he added.

People in the study lived in North America, Europe, Japan, Pakistan and Australia, and people of non-European ancestry made up just 35% of the participants. Future studies with a more diverse sample could help clarify the significance of the findings.

“It is clear that we need more follow-up studies to elucidate the mechanisms of increased stroke risk,” Kittner said.

The authors say strokes in young adults are less likely to be caused by the buildup of fatty deposits in the arteries (a process called atherosclerosis) and more likely to be caused by factors related to clot formation.

The study also found that people with type B blood were about 11 percent more likely to have a stroke than people without strokes, regardless of their age. The genetic sequences of blood types A and B were also associated with a slightly increased risk of blood clots in the veins, which is called venous thrombosis.

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