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Cervical Cancer During Pregnancy: Management and Outcomes
Objective: This study aims to describe cervical cancer during pregnancy (CCP) and investigate factors associated with survival outcomes.
Methods: This retrospective matched study included CCP patients from May 2007 to August 2021 and matched non-pregnant cervical cancer patients (1:2) based on age (±5 years), year at diagnosis (±2 years), histological type, and stage (2018 FIGO).
Effect of the HPV Vaccination Program on Incidence of Cervical Cancer
Results: In England,29,968 women aged 20-64 years received a diagnosis of cervical cancer and 335,228 a diagnosis of CIN3 between 1 January 2006 and 30 June 2020. In the birth cohort of women offered vaccination routinely at age 12-13 years, adjusted age-standardized incidence rates of cervical cancer and CIN3 in the additional 12 months of follow-up (1 July 2019 to 30 June 2020) were …
Cervical Cancer in Pregnancy: Diagnosis, Staging, and Treatment
Consequently, the predicted reduction in cervical cancer rates is as high as 55% in women aged 25-29 years, with the peak age of cancer diagnosis shifting from 25-29 years in 2011-2015 to 55-59 years in 2036-2040. by extrapolating these population models of incidence trends …
Findings:
- Cervical cancer during pregnancy is associated with notable maternal and delivery risks, though, neonatal outcomes are largely unaffected.
- These findings highlight the importance of specialized care for pregnant women diagnosed with cervical cancer, as effective management requires a multidisciplinary team specializing in oncological, obstetrical, and neonatal care.
Guidance for Healthcare Providers and Expectant Mothers:
As more women choose to have children later in life, this research offers critical guidance for healthcare providers and reassurance for expectant mothers facing a cervical cancer diagnosis.It also highlights the need for further studies to understand the long-term health outcomes for children born to mothers with cervical cancer, as well as the potential effects of cancer treatments during pregnancy.
Source:
journal reference:
Samuels, A., et al. (2025). maternal, delivery and neonatal outcomes in women with cervical cancer. A study of a population database. Oncoscience. doi.org/10.18632/oncoscience.613.
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Cervical Cancer During Pregnancy: Management and Outcomes
Objective: This study aims to describe cervical cancer during pregnancy (CCP) and investigate factors associated with survival outcomes.
Methods: This retrospective matched study included CCP patients from May 2007 to August 2021 and matched non-pregnant cervical cancer patients (1:2) based on age (±5 years), year at diagnosis (±2 years), histological type, and stage (2018 FIGO).
Effect of the HPV Vaccination Program on Incidence of Cervical Cancer
Results: In England, 29,968 women aged 20-64 years received a diagnosis of cervical cancer and 335,228 were diagnosed with CIN3 between 1 January 2008 and 9 December 2017.This research offers critical guidance for healthcare providers and reassurance for expectant mothers facing a cervical cancer diagnosis.It also highlights the need for further studies to understand the long-term health outcomes for children born to mothers with cervical cancer,and also the potential effects of cancer treatments during pregnancy.
Source:
journal reference:
Samuels, A., et al. (2025). maternal, delivery and neonatal outcomes in women with cervical cancer. A study of a population database. Oncoscience. doi.org/10.18632/oncoscience.613
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Interview: Cervical Cancer During Pregnancy – Management and Outcomes
We had the prospect to interview Dr. Emily Thompson, a renowned medical oncologist, specializing in pregnancy-associated cancers. Dr. Thompson shares her insights on cervical cancer during pregnancy,the implications for mothers and their children,and the importance of future research.
Editor: Can you provide some background on cervical cancer during pregnancy and its overall incidence rate?
Dr. Emily Thompson: Cervical cancer during pregnancy, often referred to as cervical cancer during pregnancy (CCP), is relatively rare, although it can present unique challenges due to the delicate balance required between maternal and fetal health. The incidence is approximately 1-2 cases per 1,000 pregnancies worldwide.
Editor: What are the most critically important factors influencing the survival outcomes of women diagnosed with cervical cancer during pregnancy?
Dr. Emily Thompson: Several factors can influence survival outcomes. Key factors include the stage of cancer at diagnosis, the age of the mother, and the specific management strategy chosen for both the mother and the fetus. Timely diagnosis and personalized treatment plans play a critical role in improving survival rates.
Editor: How do treatment options differ for pregnant women with cervical cancer compared to non-pregnant patients?
Dr. Emily Thompson: The management of cervical cancer during pregnancy is complex and typically involves a multidisciplinary team, including oncologists, obstetricians, and neonatologists.Treatment options often need to balance maternal health with fetal outcomes. While surgery and radiation therapy are commonly used in non-pregnant patients, they may be adjusted or delayed during pregnancy to avoid harming the fetus. Chemotherapy protocols are also modified to minimize risk.
Editor: What are the potential long-term health outcomes for children born to mothers with cervical cancer, and what are the challenges in this research area?
Dr. Emily Thompson: The long-term health outcomes for children born to mothers with cervical cancer require further study. While many children born to these mothers do not experience adverse effects, some may face increased risks due to in-utero exposure to treatments. Research is needed to better understand these potential long-term effects and to develop guidelines that optimize treatment strategies while protecting child health.
Editor: How does the HPV vaccination program impact the incidence of cervical cancer, and could it perhaps lower the rates of cervical cancer during pregnancy?
dr. Emily Thompson: The HPV vaccination program has been instrumental in reducing the incidence of cervical cancer globally. As vaccination rates increase, we expect to see a corresponding decline in the rate of cervical cancer, including pregnancy-associated cases. Vaccination before pregnancy is crucial in preventing future cervical cancer cases.
Editor: What are the main takeaways and recommendations for healthcare providers caring for women with cervical cancer during pregnancy?
Dr. Emily Thompson: Healthcare providers should be aware of the unique challenges and considerations in managing cervical cancer during pregnancy. Early and accurate diagnosis, personalized treatment planning, and close collaboration among healthcare teams are essential.Providing patients with comprehensive details and emotional support can definitely help navigate the complex decisions and challenges they face.
Conclusion:
In this insightful interview, Dr. Emily Thompson highlighted the intricate balance between maternal and fetal health in managing cervical cancer during pregnancy. Key factors such as timely diagnosis, personalized treatment, and long-term health outcomes for children were emphasized.The importance of the HPV vaccination program in reducing incidence and the need for further research into long-term effects on children were also underscored. Healthcare providers must be prepared to make complex decisions and provide comprehensive support to expectant mothers and their families.
