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Lowering Dementia Risk Through Cardiorespiratory Fitness

Can Fitness Be Your Brain’s Best Defense Against Dementia?

(Tianjin, China) – A groundbreaking new study from top researchers in China and Sweden suggests that your heart and lung health might be a powerful weapon in the fight against cognitive decline. The study, published in the prestigious British Journal of Sports Medicine, found that people with better cardiovascular fitness not only performed better on cognitive tests but also significantly reduced their risk of developing dementia. This held true even for individuals carrying a genetic predisposition to the condition.

This research offers a ray of hope for a global population facing an escalating dementia crisis. Maintaining good cardiovascular fitness – the efficiency with which your body delivers oxygen to muscles during physical activity – might be one of the most effective strategies for preserving cognitive function.

Researchers, from institutions like Tianjin Medical University and the Karolinska Institute, closely followed over 61,000 participants from the UK Biobank for up to 12 years.

The study participants, all between 39 and 70 years old, underwent a relatively simple six-minute stationary bike test to measure their cardiovascular fitness levels. This submaximal exercise test, unlike more strenuous methods, makes it more accessible for people of various fitness levels.

The results were striking. Individuals with higher cardiovascular fitness exhibited superior performance in various cognitive areas, including the ability to remember to do things in the future ("prospective memory") as well as verbal, numeric memory, and processing speed.

Even more importantly, over the study period, 553 participants developed dementia. However, those with higher cardiovascular fitness levels were 40% less likely to develop any form of dementia compared to those with lower fitness.

Perhaps most notably, the study discovered that high cardiovascular fitness could delay the onset of dementia by approximately 1.5 years.

“This is a significant finding, given that even a small delay in the onset of dementia could have remarkable public health implications,” said one of the study’s lead researchers.

One of the most exciting aspects of this research was its exploration of the interaction between fitness and genetics related to dementia risk. Researchers used a "polygenic risk score," a measure of an individual’s genetic susceptibility to Alzheimer’s disease, to categorize participants into low, moderate, and high genetic risk groups.

Surprisingly, even among people with a moderate to high genetic risk for dementia, those with higher cardiovascular fitness demonstrated a
35% lower risk of developing the condition compared to their less fit counterparts.

This finding suggests that maintaining physical fitness may help offset some of the genetic cards we’re dealt when it comes to cognitive decline – promising news for individuals with a family history of dementia.

The researchers acknowledge that their study population was predominantly white and from less socioeconomically deprived areas. While this broad representation enhances the generalizability of the findings, they speculate that the benefits of cardiovascular fitness could be even more pronounced in more diverse populations.

Taking Action for a Fitter Mind

The study’s takeaway is clear: maintaining a good cardiovascular fitness level isn’t only about physical well-being – it’s an investment in your cognitive future. Although we can’t control our genetic predisposition to dementia, we can positively influence how our bodies react to these predispositions through lifestyle choices.

"The great news is that enhancing cardiovascular fitness doesn’t require extreme measures," explains a leading exercise physiologist, not involved in the study. "Regular aerobic activities like brisk walking, swimming, cycling, or dancing can help maintain and improve cardiovascular fitness. Consistency and gradually building up endurance over time are key."

As the world faces a growing aging population and a concerning rise in dementia cases, this research offers a hopeful message: While we can’t turn back the clock on aging, we might be able to keep our cognitive engines running smoother, for longer, simply by keeping our bodies fit. It seems that when it comes to brain health, the old saying rings true – a healthy body truly promotes a healthy mind.

smiling multiethnic senior athletes synchronous exercising on step platforms at gym

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