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Chinese Biotech Firm Claims Breakthrough with Stroke Treatment: 24-Hour Golden Window?
A new drug for ischemic stroke shows potential to significantly extend the treatment window, according to recent clinical trial results announced by Taiwanese biotech company Sheng De (Shunyao) Group. The phase II trial data in China for LT3001, a novel treatment developed in partnership with Shanghai Pharmaceuticals, points to improved recovery for patients receiving the drug up to 24 hours after a stroke.
"The groundbreaking aspect is that, unlike traditional thrombolytic drugs like rt-PA which have a limited 4.5-hour window due to bleeding risks, LT3001 could potentially rewrite stroke treatment history by extending that window to 24 hours without increasing the risk of bleeding," stated a Sheng De representative.
Traditional thrombolytic drugs, while effective, have frustrated doctors and patients due to the narrow timeframe for usage. This new drug could drastically change the scenario.
The trial, a multi-center, randomized, double-blind, placebo-controlled study, focused on evaluating the safety and efficacy of LT3001 in acute ischemic stroke patients. While the primary endpoint was safety, including monitoring for adverse events and bleeding risks, secondary endpoints demonstrated promising results.
Sheng De highlighted a significantly higher proportion of patients receiving LT3001スマートフォン within 24 hours of their stroke achieving a ‘near-normal’ functional level (mRS 0-1) at 90 days, compared to the control group. This improvement surpasses the efficacy seen with typical thrombolytic drugs in previous trials.
While these results are encouraging, larger studies are needed to confirm LT3001’s long-term safety and efficacy. However, the prospect of a 24-hour window for stroke treatment excites the medical community, potentially saving countless lives and mitigating the devastating effects of this prevalent condition.
Sheng De is currently pursuing partnerships with international pharmaceutical companies to advance LT3001’s development globally.
[Image: The golden treatment time could be extended to 24 hours! The second phase of a new stroke drug in China has shown promise in curing blindness. (Source: Shunyao)]
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2024-11-29 09:05:00
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