Watch out for cardio-reno-metabolic syndrome: what it is and why it’s important to intervene quickly

Sometimes different “irregular” conditions of our organism can lead to pathological conditions that should not be underestimated; one of those is the Cardio-reno-metabolic syndrome (or Cardionephrometabolic Syndrome) can create a dangerous domino effect in patients. It is necessary to recognize this state and act quickly, which is why the topic was recently addressed in a document entitled Travel through chronicity.

What is Cardio-Reno-Metabolic Syndrome, and why does it worry doctors so much? This is the sum of various conditions that are present in our organism, relationships that may be dangerous for our health. theAmerican Heart Association (AHA) defines this syndrome as a systemic disorder in which metabolism, kidney disease and the cardiovascular system interact. Three states that are already very dangerous to take alone, but in this case create relationships to the point of causing multiple organ dysfunctions increasing mortality.

The origin of everything, doctors explain, lies in excess weight and the accumulation of adipose tissue, especially on the abdomen. This translates to a metabolic dysfunction. Adipokines (molecules synthesized and produced by adipose tissue) are produced which cause pro-inflammatory and pro-oxidative action that damages various tissues, from liver to heart. . Insulin resistance and hepatic steatosis can also occur. Unfortunately it’s a chain reaction that, in the long run, leads to subclinical coronary atherosclerosisthus damage the myocardium, with a possible heart attack, up to kidney pathology (in this case we are talking about kidney failure). The end result is disability, and then death of the patient.

Treatment of this syndrome is divided into different stages. According to the stadium, thetherapeutic approach.

1. Level 1. Accumulating excess adiposity;

2. Level 2. Entry into the view of risk factors (metabolic and renal);

3. Level 3. Subclinical cardiovascular disease with other risk factors for cardio-reno-metabolic syndrome, or chronic kidney disease risk, or high 10-year cardiovascular disease risk;

4. Stage 4. Clinical cardiovascular disease along with risk factors for the syndrome.

Since the syndrome comes from a relationship between factors and pathologies, intervention as soon as possible is more fundamental than ever. In fact, one of these diseases is enough to risk the onset of another. It is worth monitoring diabetes, kidney failure and heart failure, which cannot be considered separately. The danger of triggering a chain reaction is always around the corner. That’s why it seems like the solutiona holistic approach to the patient and the interdisciplinary communication.

“It is essential to act quickly to ensure effective and sustainable therapeutic management of these pathologies, so that the

quality of life for patients and reduce the burden on the health care system” he said to him Republic the professor Loreto Gesualdopresident of Italian medical-scientific societies (FISM).