Refeyn Unveils Advanced Microfluidics and Calibration Standards for Mass Photometry
Refeyn, a leader in mass photometry innovations, has elevated the capabilities of bioanalytics with the launch of an expanded consumables portfolio. Highlighted by next-generation microfluidic chips and a new protein calibration standard, these advancements promise not only to enhance the efficiency of mass photometry but also to broaden its applicability across various scientific fields.
Revolutionizing Bioanalytics with Cutting-Edge Technology
The recent enhancements to Refeyn’s MassFluidix® HC microfluidics system include a 2nd generation microfluidic chip, which facilitates rapid sample dilution and conducts mass photometry measurements across five channels—all within an impressive span of under 37 milliseconds. This allows scientists and researchers to characterize highly concentrated samples effectively, providing critical insights into low-affinity and transient biomolecular interactions.
With the redesign of the channel architecture eliminating the need for a bubble trap and incorporating user-friendly luer connectors, Refeyn has focused on improving the user experience. The new microfluidics chips, now individually packaged for convenient access, signal a commitment to simplifying laboratory workflows.
Enhanced Software Integration for a Streamlined Process
To further improve usability, Refeyn has seamlessly integrated software functionality with its AcquireMP mass photometer control platform. Researchers will benefit from a new automatic microfluidic chip channel detection feature, reducing the likelihood of operational errors and ensuring precise measurements.
The upgraded MassFluidix HC system stands out by enabling the characterization of samples under conditions that are typically challenging. This capability is particularly beneficial for industries employing techniques that rely on higher concentrations, such as cryo-electron microscopy (cryoEM) and X-ray crystallography. By facilitating the analysis of weak affinity protein-protein interactions and complex biomolecules like PROTACs, Refeyn ensures that advanced mass photometry is within reach for a wider array of applications.
A New Standard in Calibration
In addition to the enhancements to the microfluidics system, Refeyn introduced the MassFerence® P1 protein standard as part of its commitment to quality and precision in mass photometry measurements. This new calibrant complements the existing range of MassFerence® standards, allowing researchers to achieve calibrated results for protein measurements spanning 90 to 1000 kDa. Through this innovation, Refeyn aims to minimize challenges associated with calibration, ensuring that experimental results are both reproducible and reliable across different instruments and laboratories.
Commitment to User-Centric Design
Gerry Mackay, CEO of Refeyn, emphasized the company’s dedication to meeting the needs of its customers. “These new products reflect our commitment to responding to customer needs and providing the best possible experience for all users of mass photometry technologies. We’re aimed not just at optimizing efficiency and quality but at making mass photometry useful for a wider range of samples.”
Camille Hetez, Director of Consumables at Refeyn, added, “By using consumables that we’ve developed specifically for Refeyn instruments, our customers can benefit from hassle-free measurements, with less time needed for sample prep and more confidence in their mass photometry biomolecular analysis results.”
Impacts on the Technology Industry
As mass photometry technology evolves, its implications extend into various sectors, including pharmaceuticals, biochemistry, and molecular biology. The introduction of these enhanced consumables can reduce experimental times, increase reliability in results, and ultimately contribute to more efficient research cycles. This positions Refeyn as a pioneering force in bringing cutting-edge mass photometry technology to both established and emerging applications, heralding a new era of biomolecular analysis.
The advancements by Refeyn cultivate an environment that encourages innovation and adaptation within the scientific community. As researchers seek more efficient methodologies for biomolecular analysis, these enhancements are likely to become integral to their workflows.
Readers are invited to share their thoughts on these new developments in the comments below. How do you foresee the advancements in mass photometry affecting your research or industry?