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A team of scientists from Rice and Texas A&M Universities in United States achieved an epoch-making discovery, following a study published in the prestigious journal Nature. American scientists have developed a new method by which they destroy 99% of cancer cells with the help of vibrating molecules.
Stimulating aminocyanine molecules with near-infrared light (NIR) caused them to vibrate in sync, enough to rupture cancer cell membranes, according to Science Alert.
Aminocyanine molecules are already used in bioimaging as synthetic dyes. Commonly used in small doses to detect cancer, they remain stable in water and are very good at attaching to the outside of cells.
The research team from Rice University, Texas A&M University and the University of Texas, said the new approach is a significant improvement over another type of molecular cancer-killing machine previously developed, called Feringa-type motors, which could break and problematic cell structures.
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“It’s a whole new generation of molecular machines that we call molecular jackhammers,” Rice University chemist James Tour said when the results were published in the journal Science.
“They are over a million times faster in their mechanical movement than previous Feringa engines and can be activated with near-infrared light rather than visible light.”
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The use of near-infrared light is important because it allows scientists to penetrate deeper into the body. Bone and organ cancer could be treated without the need for surgery to reach the cancer growth.
In tests on cancer cells grown in the laboratory, the molecular jackhammer method recorded a 99% rate of cell destruction. The approach was also tested on mice with melanoma tumors, and half of the animals got rid of the cancer.
The structure and chemical properties of aminocyanine molecules mean that they remain in sync with the right stimulus, such as near infrared light. “What needs to be emphasized is that we have discovered another explanation for how these molecules can work,” said chemist Ciceron Ayala-Orozco of Rice University in the United States.
“This is the first time that a molecular plasmon has been used in this way to excite the entire molecule and actually produce mechanical action used to achieve a specific goal – in this case, rupturing the cancer cell membrane.”
“This study is about a different way to treat cancer using mechanical forces at the molecular scale,” said Ayala-Orozco.
Let’s mention that infrared (IR) light is the light found just beyond what is visible to the human eye. Near infrared (NIR) light is the wavelength section of electromagnetic radiation (EMR) closest to the normal range, but just beyond what we can see.
2024-04-05 23:13:28
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