What you need to know:
A new reverse vaccine has made our body “forget” what it has learned so that it stops attacking healthy cells in autoimmune diseases.
In extremely simple terms, we know that a vaccine teaches your body what threats look like for what antibodies are created; With them, your immune system learns to fight diseases. So why a reverse vaccine Could it be the medical revolution of the year?
It sounds almost ridiculous, doesn’t it? Why would we want a reverse vaccine that, instead of teaching your body, helped it forget?
Photo: Elizabeth Ruiz-Cuartoscuro.
Well, that could be the exact response we were hoping for against the autoimmune diseases. Diseases that have haunted millions such as multiple sclerosis, lupus, rheumatoid arthritis o to Diabetes type 1.
Understanding autoimmune diseases
Again with a summary in extremely simple terms: the autoimmune diseases, such as multiple sclerosis, lupus, rheumatoid arthritis or type 1 diabetes, are those in which your defense system is wrong.
They are diseases in which your immune system ends affecting healthy cellsconfusing them with threats.
Medical revolution: They create a ‘reverse vaccine’ against autoimmune diseases / Photo: Pexels
These autoimmune diseases have confounded medical specialists for years. They affect millions of people, they impact more and more patients and to finish it off, the reasons for their existence remain not completely clear.
The revolutionary reverse vaccine
This is where the unexpected medical revolution arrives. At the Department of Molecular Engineering at the University of Chicago, they developed a reverse vaccine what —exactly as its name explains—rather teaching you new antibodies makes your body forget them.
The scientists behind this project explained that they used a technique in the liver to exploit the work of T cells in the immune system.
In his study published by the journal Natureexplained that the function of the T cells of the immune system is to recognize unwanted elements —such as viruses, bacteria or cancer cells— and eliminate them. Once they attack, they remember it forever to eliminate them faster in the future.
Medical revolution: They create a ‘reverse vaccine’ against autoimmune diseases / Photo: Pexels
But since in autoimmune diseases the T cells target the wrong target, attacking healthy cells, the reverse vaccine makes them forget them: marking your cells as “friends”.
“The idea is that we can join any molecule to teach the immune system to tolerate it”explained the scientist behind this advance. “Instead of boosting immunity like a vaccine does, we can very specifically suppress it with a reverse vaccine.”
Currently, the experiments with this reverse vaccine are in preclinical stages, serving celiac patients; However, according to the promising results of the study, they could soon advance with other immune diseases.
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2023-09-24 12:15:00
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