A study has found that depression can directly affect type 2 diabetes, which affects 500 million people worldwide.
On the 7th (local time), a research team led by Professor Inga Prokopenko of the University of Surrey, UK, announced the results of a study that found depression may cause type 2 diabetes. The research team suggested that causes of type 2 diabetes include depression along with obesity, inactivity, and family history, and that people with a history of depression should be supported in diagnosing and preventing type 2 diabetes.
The study used a statistical technique called ‘Mendelian randomization’ to study 34 people from the UK and Finland, including 19,000 people with type 2 diabetes, 5,000 diagnosed with depression, and 153,000 self-reported depression. It analyzed the genetic and health data of more than 10,000 people.
The research team paid attention to seven genetic variations that cause type 2 diabetes and depression. These genes affect insulin secretion or inflammation in the brain, pancreas, or adipose tissue, and these biological changes increase the incidence of type 2 diabetes following depression, the research team explained.
Weight gain from depression may also play a role in type 2 diabetes, the researchers note. Obesity is a leading cause of diabetes.
It has been known for some time that people with type 2 diabetes are about twice as likely to suffer from depression as the general population. It is also well known that people with depression have a higher risk of developing type 2 diabetes.
However, the relationship between depression and type 2 diabetes remains unclear until now. The research team found that depression increases the incidence of type 2 diabetes, but added that it did not find a cause of depression in diabetes. However, the research team believed that the burden of suffering from type 2 diabetes could be a factor in causing depression.
Dr Elizabeth Robertson, lead investigator at Diabetes Research UK, which funded the study, said: “This study reveals that depression may contribute to the development of type 2 diabetes, enabling healthcare professionals to improve care and support for people with a history of depression. and may help prevent type 2 diabetes.”
The results of this study were published in the Journal of the American Diabetes Association. ‘Diabetes Care’was published on
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2023-09-07 08:54:56
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