The kidneys filter all the blood in the body every 30 minutes to remove toxins and excess fluids, but patients with diabetes can experience difficulties in their normal functioning.
Chronic kidney disease occurs when the kidneys are damaged and no longer filter the blood as well as before. This means that waste and excess fluids can build up in the body, where they can contribute to chronic diseases, including heart disease and stroke.
Researchers have discovered a new biomarker in urine – other than albumin – that could help diagnose kidney failure 5-10 years earlier. The study published in the specialty magazine The Journal of Clinical Investigation and cited by 360medical.ro reveals that as the disease progresses, the kidneys lose more and more of their functionality until they stop working, a stage known as insufficiency renal.
To survive, patients with kidney failure need kidney transplants or dialysis – (an external machine that filters/cleans the blood). Currently, albumin – a protein produced by the liver – is considered an important diagnostic marker for diabetic nephropathy (diabetic kidney disease).
However, up to 50% of patients with diabetes mellitus at high risk of BCR and renal failure have low levels of albumin in the urine.
New biomarkers for kidney failure could help doctors diagnose and treat the disease before it progresses to more serious later stages.
Recently, researchers investigated whether urinary levels of adenine, a metabolite produced by the kidneys, could predict kidney disease in people with diabetes. They found that higher levels of adenine were linked to higher rates of kidney failure.
“The most important implication of this study is that we now have a powerful biomarker that could allow us to identify people with early CKD who are at risk of disease progression,” Dr. Donald A. Molony, professor emeritus at the University of Texas McGovern School of Medicine.
Many people with diabetes report excessive thirst, numbness in the hands or feet, frequent urination, unexplained weight loss, or fatigue as classic symptoms. But these are not the only symptoms that can suggest the existence of diabetes.
Scientists claim that there are other symptoms that can guide the diagnosis, in addition to the usual blood tests, such as blood sugar, the glucose tolerance test or glycosylated hemoglobin (shows the average blood sugar levels of the last 3 months), cites doctorulzilei.ro.
1. Itching and irritation of the skin (irritations tend to occur more often on the extremities)
2. Inflammation of the skin tissue and the appearance of spots on the skin (spots frequently appear in the armpit, neck and groin areas) 3. The appearance of dandruff
4. Snoring (it makes it difficult for oxygen to enter the lungs, which interrupts glucose metabolism)
5. Hair loss (alopecia)
6. Visual disturbances (increases the risk of diabetic retinopathy, which occurs when the blood vessels behind the eye become blocked).
2023-09-05 22:45:59
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