Hops.ID – Uremia is a dangerous condition that occurs when waste products associated with decreased kidney function build up in the bloodstream.
The word “uremia” means urine in the blood and refers to the accumulated effects of waste products. It can affect the whole body.
Uremia is most often due to chronic kidney disease which can lead to end-stage kidney disease, but it can also occur rapidly to cause injury and acute kidney failure.
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In addition, uremia can cause some serious health complications such as accumulation of fluids, electrolytes, hormones and metabolic problems.
If not treated immediately, uremia is usually fatal and can endanger the safety of a person’s life.
Who is most at risk for uremia?
People with chronic kidney disease are at the highest risk for uremia. Chronic kidney disease may be caused by disease within the kidney or by a more general disease. In the United States this disease is most often caused by:
- Diabetes mellitus.
- High blood pressure.
- Glomerulonephritis (damage to the kidney filters).
- Polycystic kidney disease (caused by cysts, or fluid-filled sacs, in or around the kidneys).
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What causes someone to experience uremia?
Healthy kidneys filter waste and fluids from the body through urine. The kidneys help maintain normal levels of acids, electrolytes and hormones such as Vitamin D and erythropoietin (EPO).
Damaged kidneys don’t work properly, allowing lots of toxins to build up in the bloodstream.
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Most people feel sick when kidney function is less than 15% (15 ml/min) and need to start dialysis when function is less than 10% (10 ml/min) of normal.
