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Surgery proven Weight loss It’s an effective long-term health treatment, but it can be expensive and can come with a host of unpleasant side effects, and about a third will need “follow-up surgery” or hospitalization within 5 years.
For these reasons, only about 1% of people with obesity who underwent the surgical procedure, according to Cell Reports Medicine, was quoted by New Atlas.
bile acid;
However, a new study highlights the metabolic benefits of weight loss surgery, particularly its effect on bile acid levels and the role it plays in regulating appetite.
Researchers discovered that those who had weight-loss surgery had significantly lower levels of isoursodeoxycholate bile acid, or isoUDCA, which is linked to increased appetite and poor metabolism.
When studying the bile acid levels of a group of postoperative patients in Amsterdam, as well as two other general, non-surgical groups, the researchers found that the fiber supplement naturally lowers isoUDCA levels, which could open the door to the development of a treatment that could mimic appetite reduction and improve function. Metabolism to help people Weight loss without any surgical procedures.
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new strategies
“By better understanding the complex interaction between genes, the gut microbiome and diet in regulating bile acid levels and their impact on appetite and metabolic health, perhaps new strategies can be developed to prevent diabetes,” said lead researcher Christina Minni of King’s College London. Obesity and metabolic syndrome and their treatment.
It is noteworthy that this is not the first time that scientists have turned to the gut microbiome for answers about weight loss.
But researchers from the Universities of Nottingham, King’s College London and Amsterdam have shed new light on a poorly understood benefit of bariatric surgery and appetite reduction.
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Good news
Understanding the metabolic mechanisms that lead to decreased appetite can lead to safe and effective weight loss treatment.
In turn, study co-author Tim Spector, Professor of Genetic Epidemiology at King’s College London, explained that the results of the study “highlight the key role that fiber plays in regulating appetite and metabolism.”
He also noted that “the gut microbiome and its chemical products such as bile acids show promise for reducing obesity without the need for surgical procedures.”
It is noteworthy that obesity is linked to serious conditions, including diabetes and heart disease, which can be reduced or even reversed through weight loss.
