Home » World » Dr. Theera reveals that Metformin reduces the amount of COVID-19 – Reduce the risk of hospitalization and death

Dr. Theera reveals that Metformin reduces the amount of COVID-19 – Reduce the risk of hospitalization and death

Assoc. Prof. Dr. Thira Woratanarat, Faculty of Medicine Chulalongkorn University posted on Facebook Thira Woratanarat stating that February 23, 2023

Yesterday, around the world, there were 91,058 more people, 427 more deaths, total of 679,048,196 people, 6,793,249 total deaths.

The top 5 most infected are Japan, Taiwan, Russia, South Korea and Austria.

As of yesterday, in the number of new infections, countries from Europe and Asia occupied eight of the top 10 and 18 of the top 20 globally.

The number of new infections per day around the world right now from Asia and Europe together representing 91.17 percent of the world, while the number of deaths accounted for 72.59 percent

Update knowledge of COVID-19

1. Molnupiravir cannot be used to prevent COVID-19.

The MOVe-AHEAD study included 1,500 people from 19 countries around the world. living with a family member infected with COVID-19 Evaluating the effectiveness of Molnupiravir as a preventive measure against COVID-19. In a group of people who have close contact with an infected person or not. (Post-exposure prophylaxis)

It was found that the group receiving Molnupiravir reduced the risk of developing COVID-19. 23.6% less than the placebo group, but not significantly different.

2. Death from COVID-19 That is considered a huge economic loss to the country.

Silva S et al from the United States. The results of the study were published in Scientific Reports on February 22.

Assess the social and economic impact of the loss of life from COVID-19. in the United States More than a million people

The essence found losses from COVID-19 That reduced the average life expectancy of the population by 3.08 years.

and estimated economic losses of up to 3.57 trillion US dollars

3. Metformin reduces viral load Reduce the risk of getting sick, hospitalized and dying, including Long COVID

Findings of the latest COVID-OUT Trial presented at the CROI 2023 US Conference by Bramante C of the University of Minnesota.

Study in 1323 patients from 6 hospitals

Metformin was found to reduce viral load 4.4 times better than placebo. Metformin’s viral clearance effect was comparable to Paxlovid at day 5 and better than Paxlovid at day 10.

In addition, the group receiving the drug reduced the risk of severe illness and death by 58% and the risk of long COVID-19 by about 42%.

However, other research still needs to be monitored. From all over the world that studies have been done in the same direction or not. to have more confidence and lead to wider application considerations

…live a conscious life Protect yourself regularly.

Adjust the living environment, study place, eat, drink, work place to have better ventilation.

Wearing a mask correctly can greatly reduce the risk.

No infection or re-infection is the best.

Paying attention to the health of oneself and one’s family is important

refer
1. Merck Provides Update on Phase 3 MOVe-AHEAD Trial Evaluating LAGEVRIO™ (molnupiravir) for Post-exposure Prophylaxis for Prevention of COVID-19. Businesswire. 21 February 2023.
2. Study of MK-4482 for Prevention of Coronavirus Disease 2019 (COVID-19) in Adults (MK-4482-013) (MOVe-AHEAD). ClinicalTrials.gov. Accessed on 23 February 2023.
3. Silva S et al. Assessing the impact of one million COVID-19 deaths in America: economic and life expectancy losses. Scientific Reports. 22 February 2023.
4. Metformin Linked to Reductions in COVID-19 Viral Load. Medscape. 21 February 2023.

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