The study indicated that people with type A blood are more likely to have a stroke before the age of 60 than people with other blood types.
The study, which was prepared in 2022 and included genomic research, showed a clear relationship between the A1 subgroup gene and early stroke.
The researchers pooled data from 48 genetic studies, including about 17,000 people with stroke and nearly 600,000 without. All participants ranged in age from 18 to 59 years old. , compared to a group of other blood types.
“We still don’t know why type A blood poses a higher risk,” Stephen Kittner, senior author of neuroscience and vascular sciences at the University of Maryland, said in a statement released in 2022. “It is likely that this has something to do with blood type A. deal with blood clotting factors such as platelets and cells lining blood vessels, as well as other circulating proteins, all of which play a role in blood clot formation.
People in the study lived in North America, Europe, Japan, Pakistan and Australia, while people of non-European ancestry made up just 35% of the participants.
“It is clear that we need more follow-up studies to elucidate the mechanisms of increased stroke risk,” Kittner said.
The authors say that strokes in young adults are no longer likely to be caused by the buildup of fatty deposits in the arteries (a process called atherosclerosis), but are more likely to be caused by factors related to clot formation.
The study also found that people with type B blood were about 11 percent more likely to have a stroke than people without strokes, regardless of their age, while genetic sequences of blood types A and B were associated at a slightly increased risk of blood clots in the veins. , which is called venous thrombosis.
