December 13, 2022 – Dr. Yong Phuwarawan, Head of Center, Clinical Virology Specialist Department of Pediatrics Chulalongkorn University School of Medicine Facebook messageindicate that
In the early stages when there was no vaccine We also use antibodies to help with treatment. For example, using plasma from people who have already recovered from the covid 19 disease, which has antibodies, is like giving a serum. or monoclonal antibodies to help with treatment
Later, when there was a vaccine to create antibody immunity. There is no need for plasma antibodies because the body can make antibodies from vaccines. or infection We will use this in people who are not vaccinated and have never been infected before.
Viruses continue to mutate, producing antibodies synthesized or created with the original strain. less efficient or cannot be used Up to the current strain, Omicron BA.2.75, the antibody still acceptable in our country would be The provided antibody called LAAB (Evushield) and furthermore, the virus if altered The subspecies BQ.1, BQ.1.1 or XBB are even less effective.
use of antibodies available in our homes should now be given to people with low immunity. Especially those who have been vaccinated and their immunity is not responding. Including chronic renal failure patients Immunosuppressant organ replacement patients cancer patients undergoing treatment with drugs or radiation that affect immunity There are quite a number of them.
LAAB antibodies can also be used in treatment. similar to original plasma In risk groups who have never been vaccinated before or who have received 1 or 2 doses of vaccine because the immune level may be low or not. Initial administration of antibodies after infection will reduce the severity of the disease and mortality rates can be reduced.
The Ministry of Public Health currently has enough LAABs to supply such patients. The drug is very safe.
And now the disease is on the rise. Patients belonging to the above vulnerable groups Therefore, antibodies should be administered forcefully. Even when there is an infection, it should be treated with antibodies. to reduce the severity of illness and death
currently available drugs should rush to use in this ripple should not be stored because when the virus has mutated It will not work. or not useful