Ethylene glycol (EG) contamination in syrup pharmaceuticals is suspected to be the cause of hundreds of mysterious cases of acute kidney disease in Indonesia. Subsequently, the Indonesian Food and Drug Supervisory Agency (BPOM) reported that three products found contained EG contamination that exceeded the threshold.
As reported by BPOM on Sunday (10/23/2022), the three drugs are Unibebi Cough Syrup (Universal Pharmaceutical Industries), Unibebi Fever Drop (Universal Pharmaceutical Industries) and Unibebi Fever Syrup (Universal Pharmaceutical Industries).
What are the effects if ethylene glycol enters the body?
Pharmacists of Gadjah Mada University (UGM) Prof. Dr. Zullies Ikawati explained that there are three phases of the effect of ethylene glycol on the body. Not just on the kidneys, this material affects the nervous system first.
“If we assume to use those containing ethylene glycol and diethylene glycol in rather large quantities, in theory, in theory, the toxicity of ethylene glycol and diethylene glycol has three phases,” he said in a live broadcast on the Indonesian Medical Association. (IDI) Instagram account, Tuesday (25/10).
“The first phase is the central nervous system, it is like ethanol. If ethanol has a depressant effect, the central nervous system is. The second phase is cardiopulmonary. The third phase is the kidney due to the metabolic process.” , he added.
However, as Prof. Zullies explained, the effect of ethylene glycol poisoning on each person can be different. If it directly affects the kidneys, there will be symptoms of reduced urination.
Considering in many explanations, it is hinted that the typical symptom of mysterious acute kidney ailments in children is a decrease in the volume and frequency of urination. Even in some cases, urine production stops altogether.
“In fact, this phase does not always happen to everyone. Literally it is said that the phase is unpredictable. Sometimes it jumps, suddenly it goes straight to the kidneys. It depends on the speed of its metabolism. The kidneys (for example) do not pee. less “, concluded prof. Zullies.
Watch videos”Stages of the symptoms of mysterious acute kidney disorders in children “
[Gambas:Video 20detik]
(Vyp / kna)
