The result of a study was published in an international scientific journal according to which patients with atopic dermatitis, a chronic skin disease, have a high risk of contracting skin infections. In particular, there is a high risk of developing a contagious wart known as a water wart, and onset has been found to occur approximately two and a half months after atopic dermatitis diagnosis, so special attention is needed for the secondary skin infection.
The Department of Dermatology, Seoul St. Mary’s Hospital, Catholic University of Korea, Professor Ji-Hyeon Lee (corresponding co-author) and Joo-hee Han (co-first author), conducted a sequential correlation analysis together with the Kwangwoon University School of Business Administration research group, Suk-Jun Lee (corresponding author) and researcher Jae-Woong Yoon (co-first author) The relationship between atopic dermatitis and skin infection was analyzed in the current clinical setting used .
According to previous studies, patients with atopic dermatitis are known to have an abnormal epidermal function or systemic immune function, or the risk of skin infections increases due to a decrease in antibacterial peptides, biological defense material. The research team analyzed national health insurance data from 2010 to 2013 using SPM. Among them, 70,205 patients with atopic dermatitis were identified with the associated skin infection and the time of onset of skin infection was confirmed.
As a result of multiple regression analysis (statistical analysis), patients with atopic dermatitis compared with healthy controls 5,273 times for contagious warts (water wart), 2,852 times for impetigo, 2,251 times for chickenpox, 1,748 times for otitis media and 1,292 times for herpes eczema (herpetic dermatitis). The risk of viral warts infection was 1,105 times higher. In the SPM analysis, infectious warts accompanying atopic dermatitis showed the highest prevalence of 1.06% and was observed as the shortest time to onset with a mean of 77.42 days after atopic dermatitis diagnosis. .
Professor Han Joo-hee said: “Because atopic dermatitis is particularly related to impetigo, infectious mucous membrane and otitis media, caution is needed and proper prevention and management of infectious skin diseases will help prevent the worsening of atopic dermatitis. ”He said. Professor Lee Ji-hyun said: “Atopic dermatitis is a chronic disease that improves during treatment and recurs again when treatment is stopped. He pointed out. By Kim Tae-yeol
