The pregnant mother has thalassemia. What are your child’s chances? come and answer the questions Thalassemia and carrier thalassemia in pregnant women Can I have thalassemia? with protection guidelines
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Thalassemia genetic diseasethat many people may have heard and known because it can be both female and male and can be passed on from parents to children. According to statistics, around 24 million Thais, or 40 percent, have this type of normal gene in their body without symptoms. also known as “carriers of thalassemia”, most of whom do not even know they are. For those planning to have an heir may feel concerned Can thalassemia carriers have children? then ifpregnant motherisThalassemia What are the chances of an unborn child? How to prepare Let’s find the answers together.-
What are the causes of thalassemia in pregnant women?
Thalassemia or anemia with abnormal red blood cells It is a genetic disease caused by abnormalities in recessive genes. It causes the body to produce the amount of hemoglobin in red blood cells decreases. Resulting in abnormal red blood cells break easily. leading to anemia or chronic anemia And other complications may follow, such as gallstones in the gallbladder, diabetes, slow growth. have iron overload, abnormal heart and liver function, etc.
Pregnant mothers with thalassemia can be divided into 2 groups, that is, the “carriers of thalassemia” will have complete health. But there is a latent thalassemia gene. And it can be passed on to the unborn child. As for the “thalassemia disease”, symptoms will be obvious, such as pale, yellow eyes, fatigue, swollen abdomen, enlarged liver and spleen, which must receive blood on a monthly basis. The severity of the disease varies from
- mild symptoms The body is slightly pale yellow, gets sick easily and has jaundice. who must be given blood whenever he is sick
- very severe syndrome Symptoms appear at the age of 3-6 months. Babies will have yellow eyes, fatigue, short stature, dwarfism, a small body and an enlarged spleen. change of face The forehead is erect, the cheekbones are high, the bridge of the nose is flat and the teeth are protruding. If continued treatment is not carried out, death can occur.
- The most severe group Babies will have edema, difficulty giving birth, paleness, enlarged liver and spleen, and most will die in the womb or after birth. The mother is likely to be pregnant with toxicity. high blood pressure and could die
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The pregnant mother has thalassemia. Will you be with me?
Thalassemia is a dangerous disease and directly affects the expectant mother. because it can be passed from parents to children If the parents have thalassemia The chances of having a child with thalassemia are as follows:
- Both the father and the mother have thalassemia. The baby will be 100% thalassemia.
- One parent has the disease, the other is normal. 100% chance that the child is a carrier
- Both the father and the mother have latent genes or are both carriers. There is a 25% chance that your child has thalassemia, a 50% chance that your child has a latent gene or carrier, and a 25% chance that your child is normal.
- The father or mother has a latent gene or is the only carrier. There is no chance that the child has the disease. But the chance that the child has a latent gene or is a carrier is 50%, while the chance of having a normal child is 50%.
- One parent has the disease and the other has a latent gene. The probability that the child has the disease is 50% The probability that the child has a latent gene or is a carrier is 50%.
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The pregnant mother has thalassemia. Can I stop my child from taking it?
Although it appears to be a worrying disease, it can prevent thalassemia in children. The first begins with choosing a pregnancy. Couples should have a blood test to screen for thalassemia disease or not. make decisions and plans before having children But if you really want to have children, you must first get a diagnosis from a doctor. And the next step is to choose to give birth if you know your unborn baby has thalassemia. Couples should be consulted to offer options for fertility and safe delivery. Decide which method is up to the parents after a thorough explanation from the doctor. including the gestational age at that time
How to test for thalassemia in pregnant women?
Because thalassemia is a genetic disease. One of the best methods of prevention is to have blood and DNA tests before pregnancy. for the physician to assess the risk and severity of childhood thalassemia Testing for thalassemia in pregnant women can be performed by blood tests as follows:
- selection (Screening Test) This method is commonly used in general hospitals, the advantage is that it does not cost much. Rapid identification of carriers of thalassemia Results easy to interpret But cannot be distinguished as a carrier of any type of thalassemia.
- Hemoglobin type test (hemoglobin typing) This method is more expensive than the first. Because it is a test for different types of hemoglobin. This can be done in large hospitals and medical schools. that this type of examination can distinguish which type of thalassemia carrier which still requires an expert to interpret the results and there are limitations in some people who have two types of thalassemia genes.
- DNA test (DNA analysis) is also the most accurate and expensive method of blood analysis. Testing this method will take some time. but can you clearly say which type of thalassemia What are the risk possibilities? Sometimes it can also predict the severity of the thalassemia that will occur.
After the diagnosis, it was revealed that the pregnant mother and her husband were at risk of having a child with severe thalassemia. should consult a doctor to find out how severe the disease is and how to proceed with treatment
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Anyone planning to have children you already know should know how to prevent try to observe yourself together to take the couple’s hand to check thalassemia lesions first This will help reduce anxiety and be prepared for future challenges.
Thanks for the information from: medicine.swu.ac.th, chularat3.com, ram-hosp.co.th, thaihealth.or.th, rtcog.or.th
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