Desperate movement of the Spanish Government, distressed by the explosion of cases of monkeypox.
Given the increase in the number of patients in our country, which is taking the lead in Europe and is the second most affected by this disease worldwideonly behind the United States, the Ministry of Health has asked the European Medicines Agency (EMA) to evaluate “as soon as possible” if they can be administered in smaller portions intradermally to increase the vaccination capacity.
Spain, which has already reported 5,162 cases of monkey pox, of the more than 12,000 cases diagnosed throughout Europe, finds himself in a context of shortage of vaccines for all those affected. Our country has just received another 7,110 vaccines, a number that is currently insufficient.
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Not to Madrid, but…
Inside of Spain, Madrid is the region most affected by this type of smallpox, known as ‘monkeypox. This region has detected a total of 2,124 cases of monkeypox or monkeypox until this Wednesday30 more than those registered on Tuesday.
The Ministry of Health of the CAM had requested this Wednesday to the Ministry of Health and the Spanish Agency of Medicines and Health Products authorization to immunize five people with each monkeypox vaccine.
Given the shortage of this preventive treatment, it is sought that each vial multiply by five the number of beneficiaries.
However, the way to proceed to control the spread of smallpox once again confronts the Government of Diaz Ayuso with the central executive. The protocol of the Ministry of Health does not contemplate immunizing five people with each vaccine.
Vaccinating more people with a single dose is more effective than vaccinating half with two dosesMinistry of Health
“As a public health strategy, there is scientific evidence that vaccinating a greater number of people with a single dose is more effective than vaccinating half with two doses,” justifies the Ministry in a document on vaccination against smallpox. monkey, published Tuesday.
However, whatever the protocol says, the truth is that the situation invites us to explore new horizons.
follow the problem
Once the CAM proposal was discarded, the Department of Carolina Darias keep looking for solutions to the problem.
The Spanish Agency for Medicines and Health Products (Aemps) has reached this conclusion after the decision of the US regulatory agency, the FDA, to authorize the vaccine intradermally.
Although the vaccine is inoculated subcutaneously, The United States made the decision to implement a new method that will quintuple the amount of vaccines available in the country, the most affected so far by this outbreak.
Meanwhile, the traditional route of inoculation, the subcutaneous, which also requires two doses, will continue to be used for minorsin part because administration intradermally – between the layers of the skin, rather than through the skin – is a bit more complicated in children.
US authorities relied on a 2015 study, which noted that intradermal administration of a lower amount of the vaccine would provoke an immune response similar to the full dose administered subcutaneously, which would lead to an increase in the capacity of vaccination at a time of lack of dose.
Campaign marked by scarcity
The vaccines that have arrived in Spain are not enough to cover the population at risk. Therefore, only one of the two recommended is inoculated, but the first limits its effectiveness to approximately 30%.
Imvanex, developed by Bavarian Nordic, is given in two doses at least 28 days apart. As we said, the limited number of serums so far requires only one puncture, both pre-exposure and post-exposure.
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