HSE University
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Russian scientists invented sensors for early detection of cancer.
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Nationalgeographic.co.id—A joint research team from Russia has developed sensor nanophotonic microfluid whose potential applications include cancer detection, monitoring, and assessment of treatment response. Currently, the device can identify dissolved gases and liquids at low concentrations with a high degree of accuracy.
This research is a collaboration of scientists from HSE University, Skoltech, MPGU, and MISIS. A full description of the findings has been published in Optics Letters by title “Hybrid nanophotonic–microfluidic sensor for highly sensitive liquid and gas analyses” recently.
According to the World Health Organization (WHO), in 2020 the global cancer burden is estimated at 19.3 million new cases and 10 million deaths. WHO experts believe that about 30 percent of new cases are preventable, and a similar proportion can be cured with early detection of cancer.
Currently, ‘lab-on-a-chip’ is a mini sensor device capable of performing biochemical analysis which is considered as one of the most promising approaches for early detection of cancer. But now Russian researchers have developed a new hybrid nanophotonic-microfluidic sensor for the analysis of highly sensitive liquids and gases at very low concentrations in solution.
“Our study is an important step towards creating a compact lab-on-a-chip device capable of not only performing a series of blood tests but also detecting cancer biomarkers at an early stage using small amounts of patient blood,” said Gregory Goltsman, Professor at HSE University in a statement. the release.
Juan Gartner / Getty Images
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cancer cells
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“Ideally, we aim to create a small portable device that only requires a drop of blood. At the push of a button, the doctor will see the results, for example, that the parameters are normal or that further tests are needed.”
Current devices consist of a nanophotonic optical sensor on a chip combined with a microfluidic channel on the sensor surface. The liquid or gas pumped through the channel affects the dispersion of optical radiation in the highly sensitive nanophotonic device.
The liquid then changes the spectral characteristics (interaction between electromagnetic energy and the object) of the output. By examining these changes, the researcher can determine the composition of the sample.
A special feature of this device is the small size of the microfluidic channel that transmits the specimen to the sensor. This makes it possible to obtain results even from very small samples.
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