Coronary heart disease is the most common type of heart disease, the leading cause of heart attacks and the leading cause of death among both men and women worldwide.
“Inflammation is vital to protect the body from injury and infection”said Dr. Asad Shabbir, a clinical researcher at Queen Mary University in London who led the research. “However, in people with coronary heart disease, persistent inflammation can exacerbate the blockage of the arteries, worsening their condition and increasing the risk of heart attack. Our research suggests that a daily glass of juice Beetroot could be a way to introduce inorganic nitrates into our diet to help stop harmful inflammation. ”. The British Heart Foundation (BHF) funded research was presented at the British Cardiovascular Society conference in Manchester.
Conducting the study
The team studied 114 healthy volunteers. Of these, 78 received a typhoid vaccine to temporarily increase inflammation in the blood vessels and 36 received a cream to create a small blister on the skin and cause localized inflammation.
Volunteers drank 140 ml of beetroot juice every morning for seven days. Half of them drank high-nitrate juice, while the other half drank nitrate-free juice.
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In the typhoid vaccine group, those who drank nitrate-rich beet juice had higher levels of markers of nitric oxide in their blood, urine, and saliva than those who drank nitrate-free juice.
Nitrate-rich juice also seemed to restore the function of the endothelium, the cells that line the inside of all blood vessels. The endothelium is crucial for the proper functioning of the blood vessels, but it is lost in the event of inflammation.
The researchers also found that the blisters healed faster in the group that drank nitrate-rich beet juice, and the number of inflammatory white blood cells in the fluid samples taken from their blisters was lower after three days.
Researchers believe that high levels of nitric oxide helped speed up the rate at which volunteers were able to recover from inflammation by shifting key immune cells from a state that promotes inflammation to a more anti-inflammatory state. They suggest that this could benefit millions of people with coronary heart disease.
Clinical trials are currently planned to see if a diet high in nitrates has similar effects to those seen in healthy volunteers and if they can reduce the risk of a heart attack.
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