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However, it is important to note that there is no connection with the coronavirus vaccine and the increase in hepatitis cases.
Most children who have been tested for hepatitis are under the age of five and so have not received the vaccine.
Doctors have ruled out virtually all theories that suggest a mutation in the virus could cause the disease, or that it could be due to exposure to pets.
Also the usual causes, hepatitis viruses A, B, C, D and E, are all excluded.
Hepatitis causes inflammation of the liver, which causes diarrhea, abdominal pain, nausea and vomiting.
Doctors across the country have now been advised to take liver samples from the sickest cases of hepatitis.
Doctors at the Centers for Disease Control and Prevention (CDC) said these should be taken, along with stool, throat and blood samples to check for adenovirus.
Scientists have said that the main cause of the outbreak is likely subtype 41 of the adenovirus.
Adenoviruses are spread through close contact, experts say. They can also lead to gastroenteritis and neurological disorders.
The 10 Signs of Hepatitis You Need to Know
dark urine
Pale, gray-colored poo
Itchy Skin
Yellowing of the eyes and skin (jaundice)
Muscle and joint pain
A high temperature
Feeling and being sick
Feeling unusually tired all the time
Loss of appetite
Stomach ache
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Philippa Easterbrook, of the WHO’s Global Hepatitis Program, said last week significant progress has been made with further research and some refinements of the working hypotheses.
“Right now, the leading hypotheses remain those involving adenovirus – with also still important consideration about the role of Covid, either as a co-infection or a prior infection,” she added.
Tests over the past week showed that about 70 percent of cases tested positive for adenovirus.
There are also still cases in children under the age of two with infections spread across the country.
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The CDC says this particular virus can cause vomiting and diarrhea in children, even causing respiratory symptoms similar to the common cold.
Scientists say outbreaks are more likely in densely populated states and cases are expected to continue to crop up throughout the summer.
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