Sinovac Users Don’t Be Sad! Singapore Study Brings Bad News

A Singapore study revealed that recipients of the Sinovac COVID-19 vaccine were five times more likely to experience a severe case of COVID-19 than those who received the Pfizer vaccine. The research was conducted on 2.7 million Singaporeans aged 20 years and over who received the complete Sinovac vaccine or two doses of the COVID-19 vaccine from the Chinese pharmaceutical company.

The study published on Tuesday (12/4) analyzed the effectiveness of the Sinovac vaccine for seven weeks in 2021 from October 1 to November 21, when the country was hit by the Delta variant of COVID-19.

The team, which included infectious disease experts from the National Center for Infectious Diseases (NCID) and the Singapore Ministry of Health (MOH), observed the relatively lower effectiveness of the two inactivated vaccines Sinovac and Sinopharm against COVID-19 infection compared to the mRNA vaccine. Pfizer-BioNTech and Moderna.

Those who received the Sinovac vaccine were 4.59 times more likely to have severe COVID-19 symptoms compared to those who received the Pfizer-BioNTech vaccine. Sinovac users were also 2.37 times more likely to be infected compared to those who used the Pfizer-BioNTech vaccine.

Severe illness or symptoms of COVID-19 were defined as patients requiring oxygen supplementation in the hospital, admission to the intensive care unit (ICU), to death.

The findings also show the Moderna vaccine is more effective at preventing severe disease than the Pfizer-BioNTech vaccine.

Those taking Moderna were found to be less than half (0.42) times more likely to have severe COVID-19 than Pfizer-BioNTech recipients, and they were also less likely to become infected.

According to a report from the US Centers for Disease Control and Prevention, the higher effectiveness of the Moderna vaccine is likely due to the higher mRNA content in the COVID-19 vaccine and the longer time interval between injections.

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