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US scientists have found a hitherto undetected vulnerability in the flu virus. The new discovery, published in the journal Nature, could eliminate the need to be vaccinated against the flu every year.
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Scientists at Scripps Research, the University of Chicago, and the Icahn School of Medicine are in public grip In their research on the influenza virus, known as the influenza virus, they discovered an unknown vulnerability of the virus.
RATIONAL Aces DESIGN HAS BEEN OPENED
Senior author Andrew Ward, professor of Biology at Scripps Research, said of their new discovery, “It’s always very exciting to discover a new zone of vulnerability in a virus because it paves the way for rational vaccine design, and despite all these years of effort on the flu vaccine, there’s still something new to discover.” it shows.” said.
FLU VACCINES THAT CHANGE EVERY YEAR MAY BE DATE
Since the flu is a virus that constantly mutates, the flu vaccines used today are updated every year according to the new typings determined by the WHO.
The reason for this can be briefly explained as follows: Today’s flu vaccines ‘hemaglutinin’ well ‘HE HAS’ It targets the head of the protein. This part of the virus is one of the most variable parts and is open to mutation. In other words, the vaccine needs to be updated every year according to new mutations.
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ANTIBODIES LINK TO THE NON-MUTATING PART OF THE VIRUS
During their research, scientists discovered that some antibodies can bind not only to the head part of the protein, which is constantly mutating, but also to the stem part, which is less variable.
your team ‘anchor’ The antibodies that bind to this long-neglected part of the virus, which he calls the virus, provide hope for a new universal vaccine.
VACCINES THAT ARE LESS AFFECTED BY MUTATION
The new universal flu vaccine is currently in early clinical trials. The vaccine, which was tested on mice, provided strong protection against infection by three different viruses. Senior author Patrick Wilson of the University of Chicago gave the good news and “By identifying common regions across multiple variants, we can design vaccines that are less affected by mutations.” said.
650K PEOPLE DIE EVERY YEAR
Commonly called the flu Influenza is a contagious viral infection that attacks your respiratory system, nose, throat, and lungs. In most cases, the flu goes away on its own, but sometimes it can lead to fatal complications.
According to estimates by the World Health Organization, the flu kills between 290,000 and 650,000 people a year. Young children under 5, adults over 65, pregnant women, and people with compromised immune systems are at higher risk of developing flu complications.
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