jatimnow.com – Diabetes is one of the diseases that many Indonesians suffer, with around 10.3 million patients per year 2017.
Therefore, it is important for us to do early detection of diabetes, one of which is by looking at skin conditions.
That refers to a study from the Perelman School of Medicine at the University of Pennsylvania, which found that people with psoriasis have a higher risk of developing diabetes. Psoriasis is an inflammation of the skin characterized by a red rash, dry, thick, scaly skin that peels easily.
The 2017 study, published in the Journal of the American Academy of Dermatology, looked at the link between psoriasis and diabetes. The researchers analyzed data from 8,120 adults with psoriasis and compared it with data from 76,590 adults without psoriasis over four years.
As a result, researchers found that patients with psoriasis had at least a 21 percent higher risk of developing type 2 diabetes than those without skin conditions.
“The type of inflammation seen in psoriasis is known to increase insulin resistance, and psoriasis and diabetes have similar genetic mutations that suggest a biological basis for the association between the two conditions that we found in our study,” said study researcher Joel M Gelfand. (22/5).
The researchers determined the severity of psoriasis using the body surface area (BSA), which measures the percentage of a person’s body that has psoriasis. Those with a BSA of only 2 percent or less have a 21 percent higher risk of developing type 2 diabetes, and that risk will continue to increase for people with a higher BSA.
According to the study, patients with a BSA of 10 percent or more had a 64 percent higher risk of developing diabetes than those without psoriasis. And for every 10 percent increase in BSA beyond that, the relative risk increases another 20 percent.
“Therefore, psoriasis patients with a 20 percent BSA had an 84 percent higher risk of developing diabetes, while patients with a 30 percent BSA had a 104 percent higher risk than those without psoriasis,” said Gelfand.
According to the American Academy of Dermatology (AAD), psoriasis affects an estimated 7.4 million people in the US with the highest proportion being people between 45 and 64 years of age. Nearly 20 percent of those who develop psoriasis end up with moderate to acute diabetes.
“Clinicians may consider measuring psoriasis-affected BSA as part of standard care because it has important prognostic implications. Patients with psoriasis affecting more than 10 percent of BSA should be targeted for diabetes prevention efforts,” he said.
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