Original title: Is it effective against mutant strains?AstraZeneca vaccine phased research results released
AstraZeneca Pharmaceuticalsthe companyIt was confirmed on the 6th that preliminary research data showed that the new crown vaccine developed by AstraZeneca had “limited” protection against the mildly infected people with the mutant new crown virus originally discovered in South Africa. However, according to researchers at the University of Oxford in the United Kingdom, this vaccine appears to be effective against the new coronavirus mutant that was originally discovered in the United Kingdom.
Variants found in South Africa: limited effectiveness
United Kingdom”Financial Times“Reported on the 6th that a joint study by South Africa’s Golden Mountain University and Oxford University showed that the mutant new coronavirus originally discovered in South Africa “severely weakened” the efficacy of the AstraZeneca vaccine.
Reported that 2026 people participated in this study, half of whom participated in the control group. The median age of the subjects was 31 years old, and no subjects were admitted to the hospital or died.
In response to the above report, an AstraZeneca spokesperson said: “In this small phase I and II trial, preliminary data shows that the vaccine has limited protection for patients with mild new coronary disease. The main reason is the B.1.351 mutation (first discovered) in South Africa. Virus strain.”
The spokesperson said that given that the majority of the study subjects are young and healthy adults, the effectiveness of the AstraZeneca vaccine on critically ill patients cannot be determined at this stage, but AstraZeneca is confident that the vaccine can protect critically ill patients.
This vaccine jointly developed by AstraZeneca and Oxford University has been approved for marketing in many countries. The spokesperson said: “Oxford University and AstraZeneca have begun to improve the vaccine so that it can deal with this mutant virus. Clinical trials will be accelerated, with a view to availability in the fall.”
Variants found in the UK: Seems to be effective
The University of Oxford confirmed on the 5th that ongoing evaluations show that the effectiveness of the existing AstraZeneca vaccine against the mutant strain originally found in the UK is similar to that against other strains.
Andrew Pollard, a researcher at the University of Oxford’s New Coronary Vaccine Project, said that data from research conducted in the United Kingdom showed that “this vaccine is not only effective against the original new coronavirus, but also against the new variant virus (found in the UK) B.1.1.7.” .
The samples of the above study were collected from October last year to mid-January this year.
Sara Gilbert, another lead researcher at the University of Oxford, said: “We have always predicted that as the epidemic continues, mutant strains will become’mainstream’ and a new version of the vaccine may eventually be needed.”
An article in the British Medical Journal stated that the new coronavirus has thousands of variant strains, and only a small part of it has changed significantly. According to Reuters, what worries scientists and public health experts the most at this stage is that the three mutant strains originally found in the UK, South Africa and Brazil spread faster.
The results of the above two studies on the efficacy of the AstraZeneca vaccine against variant strains have not been published in any peer-reviewed medical journals.
(Source: Xinhua News Agency)
(Editor in charge: DF513)
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