‘Doctor Yong’ posts pros and cons 6 of the COVID-19 vaccine

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On December 10, Dr. Yong Phu Worawan, head of the Center of Specialization in Virology. Clinic, Department of Pediatrics Faculty of Medicine Chulalongkorn University Private Facebook posts “Yong Poovorawan”

COVID-19 vaccine

Advantages and disadvantages of the COVID-19 vaccine

COVID-19 vaccine when divided into vaccines

1.Lethal type

It is produced by China. It is a traditional vaccine development method for making vaccines in the past. Such as the hepatitis A vaccine, injectable polio vaccine Inactivated COVID vaccine requires cultivating large numbers of COVID-19 and destroying its power Large number of cultures Must rely on the factory facility Must be highly secure, mass production will be limited, the price will definitely be expensive. Safety is that the virus contained in the vaccine is not pathogenic. Can be given even to people with low immunity. It is a lethal, non-pathogenic vaccine. Currently, Sinopharm’s vaccine was studied in the UAE in the UAE to have an effective protection against 86%, a very satisfactory figure. It is used in China. And has been registered in the UAE.

2. The leaven type is weak.

It may be difficult because it is an emerging infection and mechanisms do not know how to weaken the power.

3.Protein antigens

It is obtained by creating proteins, especially the spikes protruding from viral bodies known as spikes, which can be produced by living organisms (recombinant protein), such as bacteria, yeasts or even plants such as tobacco, to be vaccinated and used in man In this process, such as the hepatitis B vaccine, but the COVID vaccine, the potential obstacle is the use of a good adjuvant (an immune booster) that increases the immune system. Will be in the copyright of the major pharmaceutical companies There will be barriers to formulation and adjuvant. It is being studied by large vaccine companies now. Owned by adjuvant

4. Viruses

Viral genes Only in stimulating the immune system Put into another virus That does not cause disease in humans Such vaccines are produced. And studies in humans, such as the Ebola vaccine, are being studied.

The COVID-19 vaccine we have heard of, whether it belongs to AstraZeneca-Oxford, the Chinese vaccine, we will hear it often. The advantage is rapid mass production. To make the price lower And storage using ordinary refrigerator temperature Such as vaccines used in children The performance reported remains preliminary. Still have to wait for the report upon completion of the study

5. Vaccine DNA

It has been studied for more than 20 years. Its effects are low on immunity. There are several research groups to study. Covid vaccine DNA exists because the DNA is quite durable. In easy storage and quick production

6. mRNA vaccine

We have heard a lot about Pfizer vaccines. (Pfizer), BioNTech (BioNTech) and Moderna vaccine by mRNA when entering human cells will produce a protein according to the specified mRNA pattern. Stimulate immunity The vaccine stimulates very high immunity. And is highly effective in preventing disease As news In the past, there was no vaccine made through this process. Used in humans before Vaccines in this group This will be the first vaccine to be used in humans. RNA is relatively easy to break down. The ingestion of the body to be encapsulated with nanolipid is a technique that requires such standard factory and vaccine technology, although it is easier to mass-produce, it improves the stabilization process. It is necessary to rely on temperatures from -20 degrees to -70 degrees to be used for transportation. So it’s a very problem

This is because this vaccine (mRNA) has not been used in humans before. The registration process, under normal circumstances, is certainly slow as safety concerns are concerned. At present, there is an application for emergency registration.

For anyone to choose which vaccine is to consider

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