Jakarta, Beritasatu.com – Until now, the phase 3 clinical trial of the Covid-19 vaccine, namely the Sinovac vaccine, has entered the monitoring stage of immunized subjects. This process is to ensure safety aspects, especially its effectiveness. It is expected that the efficacy will be above 50% as recommended by the World Health Organization (WHO) for approval emergency use authorization (EUA) from the POM.
Contacted Beritasatu.com, Friday (27/11/2020) night, the Head of the Eijkman Biomolecular Institute, Prof. Amin Soebandrio, said that according to WHO, as long as the efficacy is at least 50% and above, it is still acceptable. This means that people who are vaccinated are superior to those who are not vaccinated with a minimum difference of more than 50%.
“It will be even better if the difference that is currently claimed is above 90%. For example, vaccines from Pfizer and Moderna are claimed to be 90%. But this is just his claim, not yet an official announcement from the POM. In addition, there must be a WHO recommendation, not now because no one has finished the phase 3 clinical trial, “said Amin.
Amin also said, of all the Covid-19 vaccines being developed in various countries, it is not yet known how long it takes for antibodies to form in the body after a person has been immunized. Because until now the testing is still several months, so there is no complete information about immunity or antibodies produced from this vaccine.
“To find out the antibodies produced, after six months (clinical trials) then people who receive the vaccination are followed for a year, for example, up to two years,” said Amin.
However, according to Amin, the Covid-19 vaccine clinical trials were escorted and guaranteed from the start by the POM. Therefore the vaccine produced will certainly meet the quality, safety and efficacy aspects. Therefore, he appealed to the public to be vaccinated in order to increase antibodies. With the increase in antibodies, it is hoped that it will be created herd immunity, so that it can break the chain of transmission.
Immune System
Separately, the Government Spokesperson for Covid-19 Handling, Dr. Reisa Broto Asmoro, said that the human body does have a natural immune system that functions to protect the body from virus or bacteria attacks. But this immune system requires recognition of the types of germs that can cause disease. So that if a virus or bacteria enters the body in the future, then we are ready to fight and can finally prevent the disease.
“The main goal of vaccines is to make the body know and then become immune to disease. So when it enters the body, the principle is the same, namely our body immediately detects it as a threat of infection, then the body will form a system to make the immune system or antibodies needed to fight the disease, “said Reisa in the dialogue” How Vaccines Work “which was held. Committee for Handling Covid-19 and National Economic Recovery (KPCPEN), Friday.
According to Reisa, the body will remember what to watch out for, so that if there are viruses, bacteria or germs that cause disease that enter, it can be fought. One more thing, the vaccine for Covid-19 is of course with multi-layered testing and is certain to be safe for use. The Covid-19 vaccine can be optimized to prevent transmission of the Covid-19 virus.
Unlike drugs that are given after we are sick, vaccines are preventive measures so they are given when we are healthy. Vaccines create a specific or specific immune system and can fight certain diseases. But keep in mind that vaccines are not a total solution for eliminating viruses. The arrival of the Covid-19 vaccine does not mean the pandemic will end immediately.
“So, keep applying 3M’s discipline, namely wearing a mask, keeping your distance, and washing your hands with soap. Keep protecting yourself and others, ”said Reisa.
Source: BeritaSatu.com
– .
