May help higher doses of the vitamin C It is being studied in the treatment of the Corona virus in some people, but researchers exploring its potential in aging say that the main factors in effectiveness include levels of the natural carrier needed to obtain the vitamin inside cells in the body.
Age, race, gender, as well as expression levels and genetic differences of vitamin C vectors may all be effective factors for vitamin C therapy against Corona And other diseases.
Vitamin C
Researchers at the College of Medicine recommend the Georgia Center for Healthy Aging in the Journal of journal Aging and Disease“That these factors are taken into account when designing and implementing clinical trials, and when trial results are analyzed, with respect to COVID-19 As well as other cases.
And they wrote that the new nature and lack of immunity against the coronavirus prompted the world to seek effective treatments for Corona, and this includes reusing drugs with known safety features, including vitamin C, which is a booster for the immune system and an antioxidant, which made it a logical option to explore in COVID-19.
There are at least 30 clinical trials underway in which vitamin C, alone or in combination with other therapies, is evaluated against Corona Some are in doses up to 10 times the recommended dose of 65 to 90 mg per day of vitamin C.
Dr.Carlos M Isalis, co-director of the MCG Center for Healthy Aging and Head of the MCG Division on Healthy Aging, says factors such as whether or not vitamin C enters the cell are likely to be an issue with the effectiveness of treatments that ultimately show endocrine diseases. Endocrinology, Diabetes and Metabolism.
According to a co-author of the study, without enough transporters on the cell surface to obtain a water-soluble vitamin beyond the lipid layer of cell membranes, particularly large doses may aid in the formation of the vitamin around the outside of cells where it actually begins to produce oxidants. Like reactive oxygen damaging species, rather than helping to eliminate them.
However, its use in other problems caused by the virus, such as fatal sepsis, has shown its benefit in reducing organ failure and improving lung function in acute respiratory distress syndrome, which is also a major cause of illness and death due to COVID-19.
At the time their research on aging and disease was published, there were no studies published yet on the efficacy of high-dose IV vitamin studies underway for COVID-19.
Researchers have shown that some conditions, such as osteoporosis and even normal aging, are associated with a significant decrease in regulation of at least one subtype of the transporter vitamin C.
Many of the people at higher risk are at increased risk of developing diabetes COVID-19 , Including older, black and male individuals who have chronic medical conditions such as osteoporosis, high blood pressure and diabetes, due to low levels of the vitamin. C Another reason that may be considered a vitamin therapy C.
Researchers also note that patients may develop a vitamin C deficiency over the course of their illness COVID-19 Where the vitamin is consumed C At a faster rate during an active infection, insufficient levels can increase the damage from the overactive immune response.
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