Jakarta, CNN Indonesia —
Russian scientists reportedly succeeded in creating a three-dimensional model (3D) of the outer structure SARS-CoV-2 virus which gives appearance corona virus which is full of atomic dots and actively moves.
Molecular Genomics expert Riza Putranto revealed the findings of Alexey Solodovnikov from the Danish Natural History Museum, and Valeria Arkhipova from the Siberian Branch of the Russian Academy of Sciences who published the results of modeling using atomic-level precision on 4 May.
Riza assessed that from the results of this modeling, scientists can understand that the corona virus has a dynamic structure, which is called following passive movements while in the host’s body to find receptors in the target cell.
“From the results of this modeling, scientists understand that the SARS-CoV-2 virus has a dynamic structure. This dynamic structure follows passive movements while in the host’s body to find receptors in the target cell,” Riza said via Instagram account, Sunday (8/8). ).
He further said that the Spike Protein appears to provide a “twisting” movement that aims to quickly find the ACE2 receptor in the host cell, lock it and enter the cell to infect.
This is likened to Riza when she inserts the house key into the keyhole on the door, and tries to move the key so that it fits and goes in quickly.
In addition, researchers and artists who made 3D models of the surface of the corona virus also showed 3-dimensional modeling videos to show how this corona virus lives.
“SARS-CoV-2 doesn’t look like a monolithic statue. We made animations to show how the virus ‘breathes’,” Solodovnikov and Arkhipova were quoted as saying by Russian media, Nplus1.
At first glance, the shell of the corona virus looks hard. however, that’s not really the case. The shell of the corona virus is not a flat plane, but continues to move dynamically and continues to change. Then, the leg of the protein S (spike protein) in the virus that sticks like a nail into the body of the virus is stuck rigidly and doesn’t move.
In this video, both of them want to show that this virus is a fairly soft structure and show how the spike protein moves (spike protein/ protein S) pada virus corona SARS-CoV-2.
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Details of the coronavirus spike protein moiety used to infect human cells (Solodovnikov A. & Arkhipova V. via Wikimedia Commons (CC BY 4.0))- – |
They also described a model of the 25 million atoms that make up the exterior of the coronavirus. In this project, they did not create a 3D model for the inside of the virus.
He describes the structure of SarS-CoV-2 in the video in a computationally atomic order, and demonstrates the high degree of accuracy known for the structure of SarS-CoV-2 so far.
Riza said that although the Covid-19 pandemic has been running for more than 1.5 years, research on the structure of SARS-CoV-2 is still ongoing.
(can/eks)
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