—
Summary
Target
The marking of non-palpable lesions in breast cancer using seeds of 125I is an alternative to the surgical harpoon. The objective of this work is to present the results obtained with the use of seeds of 125I compared to what was the reference technique in our center, the surgical harpoon.
–
Material and method
Prospective longitudinal study that includes patients with a pathological diagnosis of breast cancer, with non-palpable lesions, candidates for primary surgical treatment in whom marking with seed was performed. 125I (2016-2018) and with harpoon (2015-2016). Histopathological analysis of the surgical piece was performed, determining the existence of affected edges. The volume of the surgical specimen was calculated.
–
Results
A total of 146 patients were included, 95 of whom underwent seed-guided lumpectomy. 125I and 51 with harpoon. The mean cube volume of the resected pieces was 135.67 cm3 vs. 190,77 cm3 (p = 0.017). The cuboid volume was 58.75 cm3 vs. 80,60 cm3 (p = 0.003). Eleven of the patients marked with seeds presented border involvement (11.6%) compared to 7 (13.2%) in the harpoon group (p = 0.084). Reexcision was performed in 9 of the seed-tagged patients and in 7 of the harpoon group (p = 0,49).
–
Conclution
The use of seeds 125I is feasible in locating non-palpable breast lesions, with a low rate of reintervention and volumes of surgical pieces significantly lower than those obtained with harpoon.
—
Abstract
Aim
Marking of non-palpable breast lesions with 125I radioactive seeds is an alternative to the use of the surgical wire. The objective of this work is to present the results that we have obtained using radioactive seed localization compared to the reference technique in our center, the wire localization of non-palpable breast lesions.
–
Material and method
Longitudinal prospective study that includes patients with histological diagnostic of breast cancer, with non-palpable lesions that are candidates to primary surgical treatment by radioactive seed localization (2016-2018) and by wire localization (2015-2016). Histological analysis of the surgical specimen was performed determining the status of surgical margins. The volume of the surgical specimen was calculated.
–
Results
A total of 146 patients were included, 95 who underwent surgery by radioactive seed localization and 51 by wire localization. The mean cube volume of the specimens were 135.67 cm3 vs. 190.77 cm3 (p = 0.017), respectively. Eleven patients who underwent surgery by radioactive seed localization showed affected margins of the specimen (11.6%), versus 7 (13.2%) of wire localization group (p = 0.084). Reintervention was performed in 9 of the patients marked with seeds and in 7 marked with wires (p = 0.49).
–
Conclusion
The use of 125I radioactive seeds is feasible in non-palpable breast lesions, with a low rate of reintervention and volumes of surgical specimens significantly lower than those obtained by wire localization.
—
Keywords
radioactive seeds
Non-palpable breast lesions
radioguided surgery
Surgical harpoon
breast-conserving surgery
–
Keywords
Radioactive seed localization
Non-palpable breast lesion
Radioguided surgery
Wire localization
Breast-conserving surgery
—
View full text
© 2019 Spanish Society of Nuclear Medicine and Molecular Imaging. Published by Elsevier España, SLU All rights reserved.
