[메디컬투데이TV] If you are depressed, your risk of having a stroke after coronary intervention increases.

[메디컬투데이=이재혁 기자] Cardiovascular disease is the leading cause of death worldwide and ranks second in Korea as well. Major cardiovascular diseases include angina pectoris and myocardial infarction, which are caused by blocking or narrowing of the coronary arteries, which is relatively safe and non-invasive, used to wide to handle.

However, a recent study by a domestic research team showed that when patients with cardiovascular disease and depression undergo percutaneous coronary intervention, the risk of stroke and early death increases.

The research team of Professor Lee Min-woo from the Department of Neurology at Sacred Heart Hospital at Hallym University, Professor Dae-young Cheon from the Department of Cardiology at Dontan Sacred Heart Hospital at Hallym University, and the -Professor Kyeong-do Han from the Department of Information, Statistics and Actuarial Science at Soongsil University conducted a study titled ‘Depression, stroke and risk of mortality after percutaneous coronary intervention: a national population-based study’ announced on the 7th that they had confirmed this information.

The research team used National Health Insurance Corporation medical data to analyze 164,198 people who underwent percutaneous coronary intervention between January 2010 and December 2017. Among them, 28,560 patients, or 17.4%, were previously diagnosed with depression .

The research team compared the incidence of acute stroke, the risk of early death, and whether coronary artery revascularization or coronary artery bypass surgery was performed after treatment for cardiovascular disease in the group diagnosed with severe -mental and the group not diagnosed with depression.

As a result, among the 28,560 patients in the depressed group, 1,468 patients (5.7%) suffered an acute stroke after percutaneous coronary intervention, whereas in the non-depressed group, 4,748 patients (3.5%) out of 135,638 patients suffered an acute stroke. After adjusting for variables, the group with depression had a 27% higher risk of acute stroke than the group without depression.

In addition, the risk of early death was 25% higher in the depressed group than in the non-depressed group. The depressed group had an 8% higher risk of having their cardiovascular vessels blocked again and undergoing a revascularization procedure or coronary artery bypass surgery. If depression lasted more than 5 years, the risk of early death was 7% higher than if depression lasted less than 5 years.

Specifically, analysis by age showed a 48% higher risk of stroke associated with depression in those under 65 years of age. This is 2.5 times higher than the increased risk of 19% for stroke related to depression in the age group 65 or older. In addition, the risk of early death in the group under 65 years of age was more than twice as high as the group over 65 years of age.

Meanwhile, patients diagnosed with depression were more likely to be older, female, or have diseases such as diabetes, high blood pressure, dyslipidemia, atrial fibrillation, and chronic kidney disease.

Professor Lee Min-woo said, “Through this study, we confirmed a new relationship between depression and the increased risk of stroke after percutaneous coronary intervention,” and added, “For patients with cardiovascular with depression, the patient’s prognosis is assessed through an introduction. – and post-procedure mental health assessment and depression management and can improve quality of life,” he explained.

He continued, “In particular, the incidence of cardiovascular disease and depression has been increasing recently among people under 65 years of age, and as this study showed that side effects greater depression in those under 65 years of age, mental health screening and active depression should be implemented in the treatment of young patients with cardiovascular disease.

At the same time, the paper was published in the October issue of the ‘Journal of Internal Medicine’, an international journal at the SCIE level.

Medical Today Video Editing Team ([email protected])

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