Health more effective treatment with fewer side effects

more effective treatment with fewer side effects

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It is a simple chemical modification which could considerably improve the efficiency but also the comfort treatment for prostate cancer. Zytiga is a drug used against metastasized prostate cancer, but its taking requires stringent conditions. So, you must be on an empty stomach two hours before taking the tablet, but also stay again without eating anything within an hour.

Sciences et futur specifies that the ingested dose must not be disturbed by the digestion process. Especially since it is not very soluble in water, once in the intestine, only 10% of the dose is absorbed. This hormone therapy therefore has a pharmacological weakness that an Australian team could have partially erased.

According to a study published in the International Journal of Pharmaceutics, a change in the chemical formula tested on mice would give promising results. Thus, Prof. Clive Prestidge and his researchers succeeded in transforming the current drug into “a oily solution encapsulated in microparticles of porous silica“.

Tests on mice then showed an efficiency increased by 40%, enough to lower the daily dosage from 1,000 mg to 700 mg in application in humans. What may seem like a simple chemist tip could simplify treatment for the most diagnosed cancer in men.

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